Ciprofloxacin is indicated for the treatment of single infection or mixed infections caused by two or more susceptible organisms. It may be used for infections caused by organisms resistant to other antibiotics, including aminoglycosides, penicillin and cephalosporins. Ciprofloxacin is indicated for the treatment of the following infections caused by sensitive bacteria. Severe systemic infections: Septicemia, bacteremia, peritonitis, infections in immunosuppressed patients with hematological or solid tumors and in patients in intensive care units with specific problems such as infected burns.

Adult Dose: The usual adult oral dose of Ciprofloxacin ranges from 250 to 750 mg twice daily depending on the severity and nature of the infection. Single oral doses of 250 or 500 mg are used for the treatment of gonorrhea, depending upon patterns of resistance. A single oral dose of 500 mg is suggested for meningococcal meningitis prophylaxis. A single oral dose of 750 mg is suggested for surgical infection prophylaxis, given 60 to 90 minutes between the procedure. Adolescents and children: Ciprofloxacin may be given to adolescents and children used 5 years or more in a dose of 20 mg per kg by mouth twice daily, up to a maximum of 750 mg twice daily. The use of Ciprofloxacin is not recommended for the growing adolescents and children. However, it is used when potential benefit is considered to outweigh this potential risk of the product. The dose should be 7.5 mg to 15 mg/kg/day (oral) in two divided doses, depending of the severity of infection. DURATION OF TREATMENT: For acute infections the usual treatment period is 5 to 10 days. Generally, in acute and chronic infection treatment should be continued for at least 3 days after the signs and symptoms of the infection have disappeared.