Acute Bacterial Exacerbations of Chronic Bronchitis and Secondary Bacterial Infections of Acute Bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae (beta-lactamase negative strains), or Haemophilus parainfluenzae (beta-lactamase negative strains) Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae (including beta-lactamase-producing strains), Moraxella catarrhalis (including beta-lactamase-producing strains), or Streptococcus pyogenes. *Pharyngitis/Tonsillitis caused by Streptococcus pyogenes. *Skin and Skin-Structure infections caused bly Staphylococcus aureus (penicillinase-and non-penicillinase-producing strains), Stereptococcus pyogenes, Escherichia coil, Klebsiella spp and Enterobacter spp "Acute bacterial Maxillary Sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae (non-beta-lactamase-producing strains only) *Urinary Tract Infections caused by Escherichla coil or Klebsiella pneumoniae. *Gonorrhea: Uncomplicated and disseminated-gonococcol infections due to Neiseria gonorrheae (penicillinase-and non-penicillinase-producing strains) in both males and femnales. Impetigo caused by Staphylococcus aureus (including beta-lactamase-producing strains) or Staphylococcus pyogenes *Switch therapy (Injectable to oral) after surgery when patients condition is improved, "Early Lyme disease (erythema migrans) caused by Borrelia burgdorferi.

Brocef-CV should be taken after food for optimum absorption. Populatlon: Adolescents and adults(13 Years and older) Infections: * Pharyngitis/Tonsillitis, Dosage: 250 mg bid daily Duration (days)10. * Acute bacterial maxillary sinusitis, Dosage: 250 mg bid daily Duration (days)10. * Acute bacterial exacerbations of chronic bronchitis, Dosage: 250 mg bid daily Duration (days)10. * Secondary bacterial infections of acute bronchitis, Dosage: 250 or 500 mg bid daily Duration (days)5-10. * Uncomplicated skin and skin structure infections, Dosage: 250 or 500 mg bid daily Duration (days) 10. * Uncomplicated urinary tract infections, Dosage: 250 mg bid daily Duration (days)7-10. * Uncomplicated, Dosage: 1000 mg once daily Duration (days) Single Dose. * gonorrhea Early Lyme Disease, Dosage: 500 mg bid daily Duration (days) 20. Populatlon: Paediatric patients(Who can shawllo tablet whole) Infections: * Pharyngiis/Tonsillitis, Dosage: 125 mg bid daily Duration (days)10. * Acute otitis media, Dosage: 250 mg bid daily Duration (days)10. * Acute bacterial maxillary sinusitis, Dosage: 250 mg bid daily Duration (days)10. Populatlon: Paediatric patients(Month to 12 Years) Infections: * Pharyngiis/Tonsillitis, Dosage: 20 mg/kg/day in two divided dose, Duration (days)10. * Acute otitis media, Dosage: 30 mg/kg/day in two divided dose, Duration (days)10. * Acute bacterial maxillary sinusitis, Dosage: 30 mg/kg/day in two divided dose, Duration (days)10. * Impetigo, Dosage: 30 mg/kg/day in two divided dose, Duration (days)10. SIDE EFFECT: Generally cefuroxime and clavulanic acid are well tolerated. However, a few side effects like nausea, Vomiting, diarrhoea, abdominal discomfort or pain may occur. As with other broad-spectrum antibiotics, prolonged administration of Cefuroxime & Clavulanic acid combination may result in overgrowth of nonsusceptible microorganisms. Rarely ((<0.20%) renal dysfunction, anaphylaxis, angioedema, pruritis, rash and serum sickness like urticaria may appear. PRECAUTIONS: Brocef-CV should be given with care to patients receiving concurrent treatment with potent diuretics and who have history of colitis. USE IN PREGNANCY & LACTATION: During Pregnancy: While all antibiotics should be avoided in the first trimester if possible, however Brocef-CV can be safely used in later pregnancy to treat urinary and other infections. During lactation: Because Brocef-CV is acceptable to use during breast feeding as it is excreted in small quantities into breast milk. However, the possibility of sensitizing the infant should be kept in mind. CONTRAINDICATIONS: Patients with Known hypersensitivity to Cephalosporins & Pseudomembraneous colitis are contraindicated.