Cefuroxime Axati (Brocef) is indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the conditions listed below: *Pharyngitis/Tonsillitis caused by Streptococcus pyogenes *Acute bacterial otitis media caused by S. pneumoniae, H. influenzae (including beta-lactamase producing strains), M. catarrhalis (including beta-lactamase producing strains) or S. pyogenes. *Acute bactarial maxillary sinusitis caused by S. pneumoniae or H. influenzae (non- beta-lactamase producing strains only) *Acute bacterial exacerbations of chronic bronchitis and secondary bacterial infections of acute bronchitis caused by S. pneumonise, H. influenzae (beta- lactamase negative strains), or H. parainfluenzae (beta-lactamase negative strains) "Uncomplicated skin and skin-structure infections caused by S. aureus (Including beta-lactamase producing strains), or S. pyogenes. *Uncomplicated urinary tract infections caused by E. call or K. pneumonise *Uncomplicated gonorrhoes, urethral and endocervical infections caused by penicillinase producing and non-penicillinase producing strains of N. gonomhoese and uncomplicated rectal gonorrhoea in females caused by non-penicillinase producing strains of N. gonorrhoeae *Early Lyme disease (Erythema migrans) caused by Borrelia burgdorferi. *Obstetric and gynaecological infection pelvic inflammatory diseases. * Other infections including septicemia and meningitis.

DOSAGE AND ADMINISTRATION Oral: Cefuroxime Axetil (Brocef) should be taken after food for optimum absorption. SIDE EFFECTS: Generally cefuroxime is well tolerated. However, a few side effects like nausea, vomiting, diarrhoea, abdominal discomfort or pain may occur. As with other broad-spectrum antibiotics, prolonged administration of cefuroxime may result in overgrowth of nonsusceptible microorganisms. Rarely (<0.20%) renal dysfunction, anaphylaxis, angioedema, pruritis, rash and serum sickness like urticaria may appear. CONTRAINDICATIONS: It is contraindicated in patients with known hypersensitivity to the cephalosporin group of antibiotics. PRECAUTIONS: Penicillin sensitivity; renal impairment, pregnancy & breast-feeding: false positive urinary glucose & false positive-Coomb's test PREGNANCY & LACTATION: Because cefuroxime is excreted in human milk, consideration should be given during treatment with cefuroxime