Products Details
Indication:
Cefuroxime Axetil (Brocef) is indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the conditions listed below:
* Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
* Acute bacterial otitis media caused by S. pneumoniae, H. influenzae (including beta-lactamase producing strains), M. catarrhalis (including beta-lactamase producing strains) or S. pyogenes.
* Acute bacterial maxillary sinusitis caused by S. pneumoniae or H. influenzae (non- beta-lactamase producing strains only)
* Acute bacterial exacerbations of chronic bronchitis and secondary bacterial infections of acute bronchitis caused by S. pneumoniae, H. influenzae (beta- lactamase negative strains), or H. parainfluenzae (beta-lactamase negative strains) "Uncomplicated skin and skin-structure infections caused by S. aureus (Including beta-lactamase producing strains), or S. pyogenes.
* Uncomplicated urinary tract infections caused by E. coli or K. pneumoniae
* Uncomplicated gonorrhoeae, urethral and endocervical infections caused by penicillinase producing and non-penicillinase producing strains of N. gonorrhoeae and uncomplicated rectal gonorrhoeae in females caused by non-penicillinase producing strains of N. gonorrhoeae
* Early Lyme disease (Erythema migrans) caused by Borrelia burgdorferi.
* Obstetric and gynecological infection pelvic inflammatory diseases.
* Other infections including septicemia and meningitis.
Dosage & Administration:
Dosage and administration oral: Cefuroxime Axetil (Brocef) should be taken after food for optimum absorption.
SIDE EFFECTS: Generally, cefuroxime is well tolerated. However, a few side effects like nausea, vomiting, diarrhea, abdominal discomfort or pain may occur. As with other broad-spectrum antibiotics, prolonged administration of cefuroxime may result in overgrowth of nonsusceptible microorganisms. Rarely (<0.20%) renal dysfunction, anaphylaxis, angioedema, pruritis, rash and serum sickness like urticaria may appear.
CONTRAINDICATIONS: It is contraindicated in patients with known hypersensitivity to the cephalosporin group of antibiotics.
PRECAUTIONS: Penicillin sensitivity; renal impairment, pregnancy & breast-feeding: false positive urinary glucose & false positive-Coomb's test.
PREGNANCY & LACTATION: Because cefuroxime is excreted in human milk, consideration should be given during treatment with cefuroxime.