It is indicated for the treatment of fungal infections of skin such as ringworm and to accelerate the desquamation. Pharmacology: This contains Benzoic Acid and Salicylic Acid in a ratio of 2:1 (6%:3%) which is also known as Whitfield's ointment. It combines the fungistatic action of benzoic acid with the keratolytic action of salicylic acid. Since benzoic acid is only fungistatic, eradication of the infection occurs only after the infected stratum corneum is shed, and continuous medication is required for several weeks to months. The salicylic acid accelerates the desquamation.

Adult & Children: Apply twice daily. It may be used in children in appropriate dose. It should not be used in neonates. Interaction: Topical salicylic acid may be absorbed and cause adverse interactions with a number of drugs. Toxicity of some drugs may be increased-acetazolamide, anticoagulants, dipyridamole, heparin, hypoglycemics and methotrexate. The efficacy of some drugs may be decreased-bumetanide, captopril & probenecid. Light kaolin can adsorb benzoic acid and its activity may be reduced. Contraindications: It is contraindicated in patients with hypersensitivity to any of its components. With topical preparations containing salicylic acid, excessive prolonged use may result in symptoms of salicylism. So it should not be used for prolonged periods, in high concentrations, on large areas of the body or on inflammed or broken skin. Side Effects: The benzoic acid can be irritant to the skin, eyes and mucous membranes. Salicylic acid is a mild irritant and application to the skin may cause dermatitis. Quick absorption of salicylic acid through the skin and slow excretion in the urine may cause acute systemic salicylate poisoning after excessive application of salicylic acid to large areas of the body. Pregnancy & Lactation: Salicylic acid is teratogenic in animal models, and although this has not been demonstrated in humans, it is not advised to use the drug in pregnancy. Because of passage in milk, it should not be used by breast-feeding women. Precautions & Warnings: It is only for external use. Care should be taken to keep the product away from contact with the mouth, the eyes and other mucous membranes to avoid irritation. It should be used with care on the extremities of patients with impaired peripheral circulation and diabetes. Skin irritation may develop. If undue skin irritation develops or increases, the patient should adjust the dosage schedule or consult their physician.